Mahesh Narayan BIOCHEMISTRY Assistant Professor B.Sc.., Bombay University, 1991 Ph.D., The Ohio State University, 1997 Postdoctoral Fellow, Cornell University Phone:(915) 747-6614 mnarayan@utep.edu PDF Format
		Narayan Research Group http://faculty.utep.edu/mnarayan

Awards and Activities European Union Travel Award American Chemical Society Honorarium Research Interests  We are interested in investigating mechanism of chaperone catalyzed protein folding reactions in order to develop small molecule mimics that can serve as chemotherapeutics. Folding studies on biomedically relevant proteins to unravel key intramolecular interactions that stabilize the native state. Similarly, we research the development of nanobiotechnological vehicles for drug-delivery		Selected Publications  · Narayan, M., Welker, E., Wedemeyer, W. J. and Scheraga, H. A. folding of Proteins” (2000) Accounts of Chemical Research 11, 737-820.     · Wedemeyer, W.J., Welker, E., Narayan, M. and Scheraga, H.A. “Disulfide bonds and protein folding,” (2000) Biochemistry 39, 4207-4216. · Welker, E., Wedemeyer, W. J., Narayan, M. and Scheraga, H. A. “Coupling of conformational folding and disulfide-bond reactions in oxidative folding of proteins” (2001) Biochemistry 40, 9059-9064.. · Welker, E., Narayan, M., and Scheraga, H. A. “Disulfide bonds in proteins” Encyc. Ref. of Genomics and Proteomics in Molecular Medicine (2003). (Ganten, D. and Ruckpaul, K, Eds) Springer Verlag. Narayan, M., et al “Evidence for the Reversal of the Oxidative Folding Paradigm” MS in   preparation. · Xu, G., Narayan, M., Kurinov, I., Ripoll, D. R., Welker, E., Khalili, M., Ealick, S. E., Scheraga, H. A. “A Localized Specific Interaction Alters the Unfolding Pathways of Structural Homologues” (2006) JACS 128:1204-1213. · Narayan, M., et al “Dissimilarity in the Reductive Unfolding Pathways of Two Ribonuclease Homologues” (2004) J. Mol. Biol. 338, 795-809.